Unsubstituted Phenols
Medchemexpress LLC HY-100583A 10mg Medchemexpress, (±)-Equol CAS:94105-90-5 Purity:>98%
Medchemexpress, HY-100583A 10mg (±)-Equol CAS:94105-90-5 (±)-Equol is the racemate of equol. Equol is a metabolite of the soy isoflavones, daidzin and daidzein. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC MIM1 509102-00-5 10mg
MIM1 (CAS 509102-00-5) is a selective small molecule inhibitor targeting the BH3-binding groove of MCL-1 an anti-apoptotic BCL-2 family protein By binding competitively to MCL-1 MIM1 disrupts its interaction with pro-apoptotic BH3-only proteins thereby neutralizing MCL-1-mediated inhibition of apoptosis In biochemical assays MIM1 displayed IC50 values of 4 7 4 8 M for competing with FITC-MCL-1 SAHBA and FITC-BID BH3 peptides In cellular models of B-ALL MIM1 induced caspase activation and cell death specifically in MCL-1-dependent cells with minimal effects on BCL-XL-dependent counterparts MIM1 is valuable for investigating the role of MCL-1 in apoptosis and for evaluating therapeutic strategies in MCL-1-driven malignancies
Medchemexpress LLC HY-N0259 5mg Medchemexpress, Epimedin B CAS:110623-73-9 Purity:>98%
Medchemexpress, HY-N0259 5mg Epimedin B CAS:110623-73-9 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Honokiol 35354-74-6 20mg
Honokiol (CAS 35354-74-6) is a small-molecule inhibitor targeting nuclear factor-kappa B (NF- B) It is designed to modulate NF- B activation induced by stimuli such as TNF and okadaic acid thereby regulating inflammatory and oncogenic signaling pathways Honokiol exerts its biological activity primarily through inhibition of NF- B activation and free radical scavenging In cell-based studies honokiol demonstrates antiproliferative and antiangiogenic activity with IC50 values ranging from approximately 10 M to 50 M depending on cell types and experimental conditions Based on these pharmacological properties honokiol holds research potential in studying inflammation signaling oxidative stress mechanisms tumor biology and angiogenesis inhibition
Medchemexpress LLC HY-W008253 100mg Medchemexpress, 5-Hydroxyindole-3-acetic acid CAS:54-16-0 Purity:>98%
Medchemexpress, HY-W008253 100mg 5-Hydroxyindole-3-acetic acid CAS:54-16-0 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC 2.4-Dihydroxyacetophenone S4762-25mg
2 4-Dihydroxyacetophenone (Resacetophenone 4-Acetylresorcinol) is a plant metabolite that can act as a qualitative reagent for ferric iron
Medchemexpress LLC HY-100744 10mg Medchemexpress, AS8351 CAS:796-42-9 Purity:>98%
Medchemexpress, HY-100744 10mg AS8351 CAS:796-42-9 AS8351 is a KDM5B inhibitor, which can induce and sustain active chromatin marks to facilitate the induction of cardiomyocyte-like cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Ko 143 461054-93-3 10mg
Ko 143 (CAS 461054-93-3) is a selective inhibitor of the breast cancer resistance protein (BCRP/ABCG2) an ATP-binding cassette transporter implicated in multidrug resistance in cancer cells By targeting BCRP Ko 143 effectively blocks BCRP-mediated drug efflux as demonstrated by an EC90 of 26 nM in cell-based assays This compound exhibits over 200-fold selectivity for BCRP compared to P-glycoprotein and MRP1 In vitro Ko 143 reverses BCRP-mediated resistance to chemotherapeutics such as topotecan and mitoxantrone enhancing their potency up to tenfold in relevant cancer cell lines Ko 143 has been used in murine models to increase systemic exposure of BCRP substrates supporting its utility in studying drug resistance mechanisms and improving chemotherapeutic efficacy in preclinical research
Apexbio Technology LLC Ko 143 461054-93-3 25mg
Ko 143 (CAS 461054-93-3) is a selective inhibitor of the breast cancer resistance protein (BCRP/ABCG2) an ATP-binding cassette transporter implicated in multidrug resistance in cancer cells By targeting BCRP Ko 143 effectively blocks BCRP-mediated drug efflux as demonstrated by an EC90 of 26 nM in cell-based assays This compound exhibits over 200-fold selectivity for BCRP compared to P-glycoprotein and MRP1 In vitro Ko 143 reverses BCRP-mediated resistance to chemotherapeutics such as topotecan and mitoxantrone enhancing their potency up to tenfold in relevant cancer cell lines Ko 143 has been used in murine models to increase systemic exposure of BCRP substrates supporting its utility in studying drug resistance mechanisms and improving chemotherapeutic efficacy in preclinical research
Selleck Chemical LLC Cinitapride Hydrogen Tartrate
Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors